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Tadalafil Stada 10mg/20mg Tablets Review: Unreviewed Tadalafil Brand from a Well-Certified Company

by Jacob Thompson 2017-03-01

Tadalafil Stada 10mg/20mg is a product containing 10 or 20 mg of Tadalafil as an active ingredient. Products with Tadalafil content are drugs used in the treatment of erectile dysfunction prevalent in geriatric males and those with underlying medical conditions [1].

Tadalafil is only one of the PDE5 (phosphodiesterase type 5) inhibitors available in the global market which are drugs prescribed for the treatment of erectile dysfunction [2].

Other known PDE5 inhibitors include Sildenafil Citrate and Vardenafil, all of which are also able to effectively aid patients suffering from ED to regain control over their erectile function.

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Since PDE5 is also present in a number of tissues aside from the penile walls, PDE5 drugs are also being used to inhibit the enzyme’s action for a number of other body tissues. Aside from ED, Tadalafil medication is also used in the treatment of the lower urinary tract symptoms of patients with benign prostatic hyperplasia (BPH) and is also used as a blood pressure-lowering drug for patients with pulmonary arterial hypertension (PAH).

There are a great number of manufacturers and suppliers of generic Tadalafil products worldwide, like the company Stada (in Germany and Vietnam), which is the producer of Tadalafil Stada 10mg/20mg [3]. the company makes the drug in tablet form only and makes Tadalafil Stada in 20 and 10 mg formulations.


STADA, the pharmaceutical company who made Tadalafil Stada, is a company which was founded in 1895 and is located in Germany [4]. STADA specializes in the manufacture and the distribution of generic and branded OTC and prescription products [4,5].

The company is known for its products such as acetaminophen, lactulose, Grippostad-C cold medicine, sun protection (Ladival), Aqualor, and Covonia [4,6]. Today, the company has expanded in about 30 countries and has around 50 sales companies in those international locations [6]. STADA currently employs about 10,400 individuals globally [5]

STADA Main Office

STADA Main Office

The company specializes in generics and biosimilars and aims to be one of the leading producers of the generics and biosimilars especially that patent expirations are more numerous than ever by the year 2020 [5]. As for the company’s accreditations, there is no specific information on the main site (Germany), but STADA Vietnam alone has various approvals from international drug regulators.

STADA Vietnam is certified by the WHO for GMP for both its Factory I and Factory II, it is also EU-GMP accredited, Taiwan PIC/S-cGMP accredited, ISO 9001:2008 certified, WHO Geneve/WHOPIR certified for its Factory II, and also Japan GMP certified for its Factory II [7].

Scientific Studies on Tadalafil

Though Tadalafil and its fellow PDE5 (phosphodiesterase type 5) inhibitors are effective in the management of erectile dysfunction in patients, their use has been limited in an on-demand basis alone, as PDE5 inhibitors are not actually cures for ED. Due to this, the patients are made to take these medications indefinitely. Studies were conducted to discover the long-term effects of Tadalafil in patients, like the study done by Montorsi et al in 2004, “Long-Term Safety and Tolerability of Tadalafil in the Treatment of Erectile Dysfunction” [8]. 1173 patients with erectile dysfunction were involved in the 24-month study and these patients were previous participants to either 8 or 12-week placebo-controlled Tadalafil studies [8]. The initial dose of Tadalafil administered to the patients was 10 mg but the dosage is variable; if the dose is ineffective, the dose is titrated to 20 mg and in the case of intolerable side effects, the dose is decreased to 5 mg [8]. Of all the initial participants, only 495 completed the 24 months of Tadalafil administration and an additional 234 completed 18 months of treatment [8]. According to the results, the drug, Tadalafil was tolerated well by the patients [8]. Adverse events noted for the use of the patients are as follows: Headache (15.8% of the patients), dyspepsia (11.8% of the patients), nasopharyngitis (11.4%), and back pain (8.2%) [8]. There were discontinuations of the treatment due to side effects and the rate of discontinuations were 6.3% for the 18-24-month study and 8.6% of the patients experienced serious side effects due to Tadalafil (although there was no pattern for treatment-related adverse reactions) [8]. Overall, the results of the study indicated the safety of Tadalafil use in 5 mg, 10 mg, and 20 mg doses, as these doses for erectile dysfunction are well-tolerated and effective [8].

Tadalafil, aside from being recommended for an on-demand or as-needed use, is also viable to be taken on a daily basis. In the past years, studies were conducted on the drug’s effectiveness and safety for the daily intake of patients with erectile dysfunction. One of those studies exploring the effectiveness of daily Tadalafil use is the study by Rajfer et al in 2007, “Tadalafil dosed once a day in men with erectile dysfunction: a randomized, double-blind, placebo-controlled study in the US”, which was a randomized, double-blind, placebo-controlled, parallel-design study involving 15 US-based centers [9]. Patients who were able to complete a 4-week period without any ED treatment were randomly assigned to a daily dose of 2.5 mg or 5 mg dose of Tadalafil or placebo in 24 weeks [9]. The results were evaluated using the IIEF-EF (International Index of Erectile Function-Erectile Function) questions 2 and 3 [9]. Based on the results of the study, Tadalafil, when taken daily, significantly improved the patients’ erectile response compared with placebo [9]. Although there were a few of the patients due to adverse reactions to the treatment, the percentage is only minimal (2.1%, placebo; 6.3%, tadalafil 2.5 mg; 4.1%, tadalafil 5 mg) [9]. Based on the results, the most common side effects observed in patients administered with the daily Tadalafil dose are back pain, viral gastroenteritis, nasopharyngitis, and influenza [9]. Overall, the daily dose of Tadalafil (both 2.5 mg and 5 mg) administered to patients is safe, effective, and well tolerated by patients [9].

Description and Mechanism of Action of Tadalafil

Tadalafil in patients works effectively in treating erectile dysfunction due to its nature. The drug is classified as a PDE5 (phosphodiesterase type 5) inhibitor which works by inhibiting the action of the PDE5 enzyme found in the penile tissue.

PDE5 enzyme is the primary factor in the destruction of the cGMP (cyclic guanosine monophosphate), which is the one responsible for the maintenance of the erectile function in the patients. The cGMP is the one mediating the relaxation of the penile smooth muscle cells, which in turn leads to the improvement of the blood flow to the spongy penile tissue. Since Tadalafil blocks the action of the PDE5 inhibitors in destroying cGMP which mediates erection, the ED patients’ erectile function is therefore restored.

Tadalafil Stada Effects for Males with Erectile Dysfunction

PDE5 medications such as Tadalafil help patients with erectile dysfunction regain their normal erectile function with their every use. Patients who suffer from impotence usually find it hard to attain and maintain their erectile response and Tadalafil specifically targets the patients’ ability to respond to sexual stimuli.

Patients can expect the result of their Tadalafil intake about 30 minutes after ingesting the drug. PDE5 inhibitors such as Tadalafil are not cures for erectile dysfunction, but patients can expect Tadalafil to improve their erectile response with every use, regardless of their ED’s etiology.

Recommended Doses and Duration of Therapy

The daily dose of Tadalafil is prescribed at either 2.5 mg to 5 mg per intake, but for the as-needed intake, Tadalafil is prescribed at 5 mg, 10 mg, 20 mg, or 40 mg, depending on the severity of the patients’ erectile dysfunction.

Since Tadalafil is no cure for ED, there is no length of treatment recommended for the patients; but, long-term use for Tadalafil (as-needed) has an established safety profile and also was proven effective [8]. There are also studies proving the effectiveness of long-term use of the daily dose for Tadalafil, although the patients are sometimes limited by the cost of treatment, especially for the brand-name medications for Tadalafil.

Side Effects and Warnings

Almost all medications have side effects, although not all patients get to experience them.

As for Tadalafil treatment, there are several side effects which patients are most likely to get from the drug: back pain, viral gastroenteritis, nasopharyngitis, influenza, headaches, and dyspepsia, as these are the side effects observed in patients who were treated with Tadalafil in recent studies [8][9].

There are more serious side effects, though; patients may experience painful erections (more than 4 hours), vision loss, vision changes, heart attack symptoms, chills, cold sweats, confusion, nausea, pain in the arms/back/neck, tinnitus, irregular heartbeat, shortness of breath, convulsions, and others which may not be listed [10]. As a general rule, patients should discontinue Tadalafil immediately and contact their health care providers on the onset of these side effects, to avoid the worsening of the symptoms.


Tadalafil, since it is a blood pressure-lowering medication, should not be taken with any hypertensive medication. The patients are also not allowed to take nitrates, cardiovascular medication, and angina medication, as these medications are also able to lower the blood pressure of the patients.

There are also other meds which are able to affect how Tadalafil works and these include antifungals, antibiotics, and HIV/AIDS medications. Patients with maintenance medication should consult their meds with their doctors to identify the meds which they should or should not take.

Customer Reviews

Tadalafil Stada 10mg/20mg did not have any customer reviews from patients or buyers who were able to use the drug. Tadalafil products have implied effectiveness, though, so it is expected that this generic drug will work almost the same way as its generic Tadalafil counterparts.

But, since not all medications are identical 100%, there may be variations in how patients respond to the medication. That’s why reviews are so important; they give other patients insight regarding the things which may not be mentioned on the drug labels or product information for a certain drug. Reviews would have been helpful in determining how patients are able to respond to Tadalafil Stada treatment.

Tadalafil Stada Price, Dosage, and Forms

Being a generic medication, Tadalafil Stada is actually cheap; the product sold by one online drugstore in Vietnam ( has the product available for only $2.66 per box of the medication. A box of Tadalafil Stada contains 2 tablets, so each of the tablets costs only $1.33 apiece.

Tadalafil Stada Price

Tadalafil Stada Price

Concerning the shipping, the drug is able to ship locally in Vietnam consumers but there is no information regarding shipping to international clients. This drugstore may be still restricted to distribute the product to international clients. Buyers from the USA, Australia, and Canada cannot avail of this drug online, but they can check whether the drug is available in their local drugstores as Tadalafil Stada is distributed by STADA in the US, the UK, European countries (Germany and others), Vietnam, and other Asian countries.

Reference List

  1. Tadalafil STADA® 10/ 20 mg. Attainable at:
  2. TADALAFIL STADA USES. Attainable at:
  3. Tadalafil Stada. Attainable at:
  4. STADA Arzneimittel. Attainable at:
  5. Overview. Attainable at:
  6. Product Selection. Attainable at:
  7. Achievements. Attainable at:
  8. Montorsi F, Verheyden B, Meuleman E, Jünemann KP, Moncada I, Valiquette L, Casabe A, Pacheco C, Denne J, Knight J, Segal S. Long-term safety and tolerability of tadalafil in the treatment of erectile dysfunction. European urology. 2004 Mar 31;45(3):339-45. Attainable at:
  9. Rajfer J, Aliotta PJ, Steidle CP, Fitch WP, Zhao Y, Yu A. Tadalafil dosed once a day in men with erectile dysfunction: a randomized, double-blind, placebo-controlled study in the US. International journal of impotence research. 2007 Jan 1;19(1):95-103. Attainable at:

Editor's Rating

Overall Score
Tadalafil Stada 10mg/20mg is the version of STADA for Tadalafil but this product, in particular, had no reviews from patients who were able to use it. But generally, Tadalafil products are effective in the management of erectile dysfunction in patients, regardless of the cause of the erectile dysfunction. But since generic brands are not 100% identical to the brand-name types, there are variations in the responses which the drug can elicit from its patients. I am still rating the drug 4 out of 5 though, and recommend the drug for the patients to purchase although the drug did not have any reviews since the company making the drug (STADA) is well-certified for its manufacturing processes and its standards for product quality. There is limited information on the online sale of the product, though; but since STADA is a global brand, the products are available locally in various parts of the world.
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